Azido(trimethyl)stannane → HCID 178441958, compound

HRID 1742110Notes

Reaction equation

HRID 1742110 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:23]#[N:24])=[CH:13][CH:12]=2)[C:8]([S:25][CH2:26][CH:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)=[N:7][N:6]=1)[CH2:2][CH2:3][CH3:4].C[Sn]([N:37]=[N+:38]=[N-:39])(C)C>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:23]3[NH:39][N:38]=[N:37][N:24]=3)=[CH:13][CH:12]=2)[C:8]([S:25][CH2:26][CH:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)=[N:7][N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5104973Azido(trimethyl)stannaneHCID 10095012HCID 10095012, compound

Product 1

HCID 178441958HCID 178441958, compoundYield 60%

Procedure

Reaction of 3-n-butyl-4-[(2'-cyanobiphenyl-4-yl)methyl]-5-(cyclohexylmethylthio)-4H-1,2,4-triazole (Step A) with trimethyltin azide according to the procedure of Example 18, Step B, gave a 60% yield of the title compound as a white solid, mp 89°-91° C., homogeneous by TLC in 4:1 CH2Cl2 --MeOH; mass spectrum (FAB) m/e 488 (M+1)+.

Sources & evidence

ORD record
ord-469966a09513449a800b8c871c763888
Source dataset
uspto-grants-1994_08
Patent number
US05336778

Reaction notes

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