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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1742159Generated: November 1, 2026

Hydroxyphenylacetic acid → Ethyl 4-hydroxyphenylacetate

https://huagongshe.com/reaction/1742159

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyphenylacetic acidHCID 127—
ReactantEthanolHCID 702—
ReactantSulfuric AcidHCID 1118—
ProductEthyl 4-hydroxyphenylacetateHCID 28310—

Reaction Steps

4-Hydroxyphenylacetic acid (50.0 g) is dissolved in ethanol (400 ml) and thereto is added conc. sulfuric acid (0.5 ml). The mixture is refluxed with stirring, and ethanol is distilled off to give ethyl 4-hydroxyphenylacetate (60 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05338482
Source datasetuspto-grants-1994_08
ORD IDord-c7b5678d9bf1405bba98f3a324811eb9
Source noteuspto-grants-1994_08