Hydrazine hydrate (1:1) → N-(2,2,6,6-tetramethyl-4-piperidinyl)-N'-aminosuccinamide

HRID 1742459Notes

Reaction equation

HRID 1742459 reaction equation
[NH2:1][CH:2]1[CH2:7][C:6]([CH3:9])([CH3:8])[NH:5][C:4]([CH3:11])([CH3:10])[CH2:3]1.C([CH:14]([CH2:18][C:19](Cl)=[O:20])[C:15](Cl)=[O:16])C.O.[NH2:23][NH2:24]>CO>[CH3:8][C:6]1([CH3:9])[CH2:7][CH:2]([NH:1][C:15](=[O:16])[CH2:14][CH2:18][C:19]([NH:23][NH2:24])=[O:20])[CH2:3][C:4]([CH3:11])([CH3:10])[NH:5]1

Participants

5

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 375244-Amino-2,2,6,6-tetramethylpiperidineHCID 218646082-Ethylbutanedioyl dichloride

Product 1

HCID 14745323N-(2,2,6,6-tetramethyl-4-piperidinyl)-N'-aminosuccinamide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-(2,2,6,6-tetramethyl-4-piperidinyl)-N'-aminosuccinamide was prepared by the reaction of 4-amino-2,2,6,6-tetramethylpiperidine with ethyl succinyl chloride followed by hydrazinolysis of the resulting ester with 85% hydrazine hydrate in methanol.

Sources & evidence

ORD record
ord-ecdcb53b045c42b6b7089987f4e42f07
Source dataset
uspto-grants-1994_08
Patent number
US05338853

Reaction notes

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