HCID 19006951, compound → HCID 15222891, compound

HRID 1742583Notes

Reaction equation

HRID 1742583 reaction equation
[O:1]=[C:2]1[C:11]2[CH:10]=[C:9]([C:12]([O:14]C)=[O:13])[CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH:16]=[CH:17][C:18]([C:20]([O:22]CC)=[O:21])=[N:19][N:3]12>Cl>[O:1]=[C:2]1[C:11]2[CH:10]=[C:9]([C:12]([OH:14])=[O:13])[CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH:16]=[CH:17][C:18]([C:20]([OH:22])=[O:21])=[N:19][N:3]12

Participants

3

Reactant 1

HCID 19006951HCID 19006951, compound

Product 1

HCID 15222891HCID 15222891, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A mixture of 2-ethyl 8-methyl 10-oxo-10H-pyridazino [6,1-b]quinazoline-2,8-dicarboxylate (0.15 g, 0.46 mmol, Example 1, Step C) in 50 mL of 10% hydrochloric acid was refluxed for 24 h. The mixture was cooled and filtered to give the titled compound as a yellow solid, mp>285° C.

Workup

  1. temperaturewas refluxed for 24 h
  2. temperatureThe mixture was cooled
  3. filtrationfiltered

Sources & evidence

ORD record
ord-8f46f6cc4bee4082a3e611d50512efc8
Source dataset
uspto-grants-1994_08
Patent number
US05340808

Reaction notes

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