Diisopropylaniline → HCID 18998499, compound

HRID 1742661Notes

Reaction equation

[CH3:1][C:2]1[C:12]2[CH:11]([C:13]([OH:15])=O)[C:10]3[CH:16]=[CH:17][CH:18]=[CH:19][C:9]=3[CH2:8][O:7][C:6]=2[C:5]([CH3:20])=[CH:4][CH:3]=1.[CH:21]([C:24]1[CH:30]=[CH:29][CH:28]=[C:27]([CH:31]([CH3:33])[CH3:32])[C:25]=1[NH2:26])([CH3:23])[CH3:22]>>[CH:31]([C:27]1[CH:28]=[CH:29][CH:30]=[C:24]([CH:21]([CH3:23])[CH3:22])[C:25]=1[NH:26][C:13]([CH:11]1[C:10]2[CH:16]=[CH:17][CH:18]=[CH:19][C:9]=2[CH2:8][O:7][C:6]2[C:5]([CH3:20])=[CH:4][CH:3]=[C:2]([CH3:1])[C:12]1=2)=[O:15])([CH3:33])[CH3:32]

Participants

Reactant 2

HCID 32484Diisopropylaniline

HCID 18998494HCID 18998494, compound

Product 1

HCID 18998499HCID 18998499, compoundYield 55.7%

Procedure

The similar procedures as in Example 1 were repeated except using 1.34 g of 6,11-dihydro-1,4-dimethyldibenz[b,e]oxepin-11-carboxylic acid obtained in Example 64 (Compound AC) in place of Compound A and 1.18 g of 2,6-diisopropylaniline in place of aniline to obtain 1.19 g of Compound 49.

Sources & evidence

ORD record: ord-739df4f53c354dcea6201e7871c1a6e7
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05340807

Reaction notes

Loading…