Diisopropylaniline → HCID 10367507, compound

HRID 1742663Notes

Reaction equation

[CH3:1][O:2][C:3]([C:5]1[C:10]2[O:11][CH2:12][C:13]3[CH:22]=[CH:21][CH:20]=[CH:19][C:14]=3[CH:15]([C:16]([OH:18])=O)[C:9]=2[CH:8]=[C:7]([CH3:23])[CH:6]=1)=[O:4].[CH:24]([C:27]1[CH:33]=[CH:32][CH:31]=[C:30]([CH:34]([CH3:36])[CH3:35])[C:28]=1[NH2:29])([CH3:26])[CH3:25]>>[CH:34]([C:30]1[CH:31]=[CH:32][CH:33]=[C:27]([CH:24]([CH3:26])[CH3:25])[C:28]=1[NH:29][C:16]([CH:15]1[C:14]2[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=2[CH2:12][O:11][C:10]2[C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][C:7]([CH3:23])=[CH:8][C:9]1=2)=[O:18])([CH3:36])[CH3:35]

Participants

Reactant 2

HCID 32484Diisopropylaniline

HCID 10335674HCID 10335674, compound

Product 1

HCID 10367507HCID 10367507, compoundYield 8.5%

Procedure

The similar procedures as in Example 1 were repeated except using 6.73 g of 6,11-dihydro-4-methoxycarbonyl-2-methyldibenz[b,e]oxepin-11-carboxylic acid obtained in Example 65 (Compound AD) in place of Compound A and 3.82 g of 2,6-diisopropylaniline in place of aniline to obtain 0.86 g of Compound 51.

Sources & evidence

ORD record: ord-48c1241752344806ba80c1cb72780350
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05340807

Reaction notes

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