反应详情

Into 20 ml of dioxane were dissolved 0.5 g of 5-(4-aminophenyl) thiazolidine-2,4-dione, and, after added 0.34 g of benzoyl chloride and further added dropwise 0.24 g of triethylamine, the mixture was refluxed for 1 hour. After cooling by standing, the reaction mixture was poured into 150 ml of ice water and the crystals deposited were collected by filtration, washed with water and dried. These were recrystallized from chloroform to obtain 0.70 g of title compound.

1. temperaturethe mixture was refluxed for 1 hour
2. temperatureAfter cooling
3. filtrationthe crystals deposited were collected by filtration
4. washwashed with water
5. customdried
6. customThese were recrystallized from chloroform