Dimethylformamide → HCID 11144709, compound

HRID 1743022Notes

Reaction equation

[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4]([CH2:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21]([N:23]([CH:30]([CH3:32])[CH3:31])[C:24]([NH:26][CH:27]([CH3:29])[CH3:28])=S)=[O:22])=[CH:3]1.CN(C=[O:37])C>>[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4]([CH2:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21]([N:23]([CH:30]([CH3:32])[CH3:31])[C:24]([NH:26][CH:27]([CH3:29])[CH3:28])=[O:37])=[O:22])=[CH:3]1

Participants

Reactant 2

HCID 6228Dimethylformamide

HCID 86748095HCID 86748095, compound

Product 1

HCID 11144709HCID 11144709, compound

Procedure

1-[3-oxo-androst-4-ene-17β-carbonyl]-1,3-diisopropylthiourea m.p. 180°-183° C., [α]D +146° (C=1, DMF).

Sources & evidence

ORD record: ord-d5544d96f9af47f19bcb434a22e17850
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05342948

Reaction notes

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