Water → HCID 88776009, compound

HRID 1743083Notes

Reaction equation

HRID 1743083 reaction equation
O.[CH3:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])=[O:20]>C(O)C>[CH3:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])=[O:20].[CH2:19]([OH:20])[CH3:18]

Participants

4

Reactant 2

HCID 962Water2×HCID 5283468Glyceryl Monooleate3×

Product 1

HCID 88776009HCID 88776009, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent3×

Procedure

The powder was formed by spray-drying a liquid emulsion. The liquid emulsion was prepared from a premix of 75 grams of water, 50 grams of dextran (average MW˜37,500), 45-grams of ethyl alcohol, and a 30-gram measure of molten monoolein. The mixture had a final ratio of 37.5% water, 25% dextran, 22.5% ethyl alcohol and 15% monoolein. Observation indicated that this mixture was an emulsion of isotropic liquid in a lamellar and/or nematic liquid crystalline continuous phase. The mixture was then pumped at a rate of 3.92 grams per minute through the liquid side of a twin-fluid atomizer, with slight adjustments being made to the flow rate to keep the temperature of the exit air in the system between 125–135° C. The liquid feed was atomized with air at a pressure of 42.6 psi (293.5 kPa). The powders produced were comprised of 5–100 μm agglomerates of 1–10 μm primary particles that are likely dextran shells coating monoolein and residual ethanol (˜10 w/w). Hydration of the powders produced mostly sub-micron cubic liquid crystalline particles in the range of at least about 0.1 m to at least about 10 m.

Workup

  1. customThe powder was formed
  2. customby spray-drying a liquid emulsion
  3. customThe liquid emulsion was prepared from
  4. custombetween 125–135° C
  5. customThe powders produced
  6. customHydration of the powders produced mostly sub-micron cubic liquid crystalline particles in the range of at least about 0.1 m to at least about 10 m

Sources & evidence

ORD record
ord-e8b69130713242b198e3ad620c94497d
Source dataset
uspto-grants-2006_03
Patent number
US07008646B2

Reaction notes

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