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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743096Generated: October 31, 2026

Ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate hydrochloride → Naloxone

https://huagongshe.com/reaction/1743096

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate hydrochlorideHCID 32328—
ReactantNaloxone HydrochlorideHCID 5464092—
SolventWaterHCID 962—
ProductNaloxoneHCID 5284596—

Reaction Steps

23.82 g tilidine HCl ½ H2O and 2.04 g naloxone HCl 2H2O are dissolved in 874 ml purified water, 124 ml ethanol (96%) and 2 ml HCl at room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07008939B2
Source datasetuspto-grants-2006_03
ORD IDord-812ec57bc9904aaeb0b61bf2afbae14d
Source noteuspto-grants-2006_03