Ammonia → HCID 67137526, compound

Participants

Reaction Steps

A mixture of 170 mg of methyl (3R,6R,7aS)-6-benzyl-6-tert-butoxycarbonylamino-5-oxohexahydropyrrolo[2,1-b]thiazole-3-carboxylate and 10 ml of a 7N NH3 solution in methanol is left to stand at room temperature overnight. The volatile constituents are stripped off in vacuo, and the residue is stirred with tert-butyl methyl ether, and the solid is filtered off with suction and dried in vacuo at 40° C.

Provenance & Evidence