反应详情

Condensation of 2-oxo-4-trifluoromethyl-1,2-dihydroquinoline-6-sulfonyl chloride (Preparation 3, 16 mg, 51 μmol) with BnNH2 (7 μL, 54 μmol), employing NEt3 (8 μL, 57 μmol) as base as delineated in Example 1, gave the title compound (18 mg, 90%): δH ((CD3)2SO) =4.00 (d, 2H), 7.05 (s, 1H), 7.10–7.20 (m, 5H), 7.50 (d, 1H), 7.95 (dd, 1H), 8.00 (d, 1H), 8.30 (t, 1H); m/z (ES−)=381.0 [M−H]−.