4-Methoxybenzylamine → HCID 10427998, compound

HRID 1743307Notes

Reaction equation

HRID 1743307 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH3:20][O:21][C:22]1[CH:29]=[CH:28][C:25]([CH2:26][NH2:27])=[CH:24][CH:23]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:27][CH2:26][C:25]1[CH:28]=[CH:29][C:22]([O:21][CH3:20])=[CH:23][CH:24]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 754524-MethoxybenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10427998HCID 10427998, compoundYield 87%

Procedure

The compound prepared in Example 3 was reacted with 4-methoxy-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 87%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-414b531c60e340869d932156ecc81829
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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