Propylamine → HCID 10265313, compound

HRID 1743317Notes

Reaction equation

HRID 1743317 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH2:20]([NH2:23])[CH2:21][CH3:22]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:23][CH2:20][CH2:21][CH3:22])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 7852PropylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10265313HCID 10265313, compoundYield 87%

Procedure

The compound prepared in Example 3 was reacted with propyl amine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 87%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-59d268ec7d7943a686e8a53f6e49c0f8
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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