HCID 2766903, compound → HCID 12009927, compound

HRID 1743333Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH2:12][CH:13]=[CH2:14])=[C:6]([CH:10]=1)[CH:7]=[N:8][OH:9].Cl[O-].[Na+]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH2:12][CH:13]=[CH2:14])=[C:6]([CH:10]=1)[C:7]#[N+:8][O-:9]

Participants

Reactant 2

HCID 2766903HCID 2766903, compound

HCID 23665760Sodium Hypochlorite

Product 1

HCID 12009927HCID 12009927, compound

Procedure

The oxidation of 5-bromo-2-allyloxybenzaldoxime using sodium hypochlorite solution to give 5-bromo-2-allyloxybenzonitrile oxide and the subsequent 1,3-dipolar cycloaddition were carried out in a static micromixer (Technical University of Ilmenau, Faculty of Machine Construction, Dr. Norbert Schwesinger, Postfach 100565, D-98684 Ilmenau) having a physical size of 40 mm×25 mm×1 mm with a total of 11 mixing stages each with a volume of 0.125 μl. The total pressure loss was about 1000 Pa.

Sources & evidence

ORD record: ord-a756163fb8ef4510bc750c0233f18722
Source dataset: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07009059B2

Reaction notes

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