Potassium Bromide → HCID 22237454, compound

HRID 1743429Notes

Reaction equation

C[O:2][C:3](=[O:26])[CH2:4][O:5][C:6]1[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:10][C:9]([O:18][CH3:19])=[CH:8][C:7]=1[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[K+].[Br-]>>[CH3:19][O:18][C:9]1[CH:10]=[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:6]([O:5][CH2:4][C:3]([OH:26])=[O:2])=[C:7]([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:8]=1

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 69628001HCID 69628001, compound

Product 1

HCID 22237454HCID 22237454, compound

Procedure

The title compound was prepared as a white solid (0.099 g, 91%) from (5′-methoxy-[1,1′;3′,1″]terphenyl-2′-yloxy)acetic acid methyl ester using a procedure similar to step 2 of Example 36, mp 143–145° C.; 1H NMR (DMSO-d6) δ 3.65 (s, 2H), 3.80 (s, 3H), 6.89 (s, 2H), 7.33–7.39 (m, 2H), 7.39–7.45 (m, 4H), 7.57–7.61 (m, 4H), 12.40–12.46 (bs, 1H); IR (KBr) 3380, 3080, 2920, 2890, 2810, 1770, 1740, 1600, 1575, 1495, 1470, 1425, 1360, 1240, 1210, 1180, 1160, 1070, 1045, 755, and 700 cm−1; mass spectrum [EI], m/z 334 (M)+; Anal. Calcd. for C21H18O4.0.25H2O: C, 74.43; H, 5.50; N, 0.00. Found: C, 74.21; H, 5.49; N, 0.09.

Sources & evidence

ORD record: ord-7905c6e0a1c54c34b3e686036fb7af2b
Source dataset: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07008636B2

Reaction notes

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