Potassium Bromide → HCID 22237461, compound

HRID 1743430Notes

Reaction equation

C[O:2][C:3](=[O:25])[CH2:4][O:5][C:6]1[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:10][C:9]([Br:18])=[CH:8][C:7]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[K+].[Br-]>>[Br:18][C:9]1[CH:8]=[C:7]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:6]([O:5][CH2:4][C:3]([OH:25])=[O:2])=[C:11]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:10]=1

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 53712941HCID 53712941, compound

Product 1

HCID 22237461HCID 22237461, compound

Procedure

The title compound was prepared as a white solid (0.062 g, 83%) from (5′-bromo-[1,1′;3′,1″]terphenyl-2′-yloxy)acetic acid methyl ester using a procedure similar to step 2 of Example 36, mp>50° C. (decomp.); 1H NMR (CDCl3) δ 3.81 (s, 2H), 7.38–7.50 (m, 7H), 7.52–7.56 (m, 5H); IR (KBr) 3400, 3050, 2900, 1730, 1565, 1495, 1460, 1420, 1210, 1060, 875, 735, 700, and 610 cm−1; mass spectrum [(+) FAB], m/z 382 (M)+, 405 (M+Na)+; Anal. Calcd. for C20H15BrO3: C, 62.68; H, 3.95; N, 0.00. Found: C, 62.25; H, 4.01; N, 0.01.

Sources & evidence

ORD record: ord-81c7b11202324cc7a961cb75c66fa7a3
Source dataset: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07008636B2

Reaction notes

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