HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | HCID 22234966 | HCID 22234966 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235081 | HCID 22235081 | 35.9% |
Reaction Steps
Using 0.51 g of (2-chloro-4-fluorobenzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.12 g of sodium hydride (60% in oil), and 0.34 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.21 g of 2-(2-chloro-4-fluorobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (44)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07011838B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-06f7fddb6add432e820971a22375922b |
| Source note | uspto-grants-2006_03 |