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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743826Generated: November 1, 2026

{[1-(3-Methoxy-2,2-dimethylpropyl)piperidin-4-yl]methyl}amine → 5-amino-6-chloro-N-{[1-(3-methoxy-2,2-dimethylpropyl)piperidin-4-yl]methyl}2-methyl-imidazo[1,2-a]pyridine-8-carboxamide

https://huagongshe.com/reaction/1743826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{[1-(3-Methoxy-2,2-dimethylpropyl)piperidin-4-yl]methyl}amineHCID 22236505—
ReactantMethyl 5-amino-6-chloro-2-methylimidazo[1,2-a]pyridine-8-carboxylic acidHCID 67550158—
Product5-amino-6-chloro-N-{[1-(3-methoxy-2,2-dimethylpropyl)piperidin-4-yl]methyl}2-methyl-imidazo[1,2-a]pyridine-8-carboxamideHCID 22236501—

Reaction Steps

The title compound was prepared according to the procedure described in the Step 6 in EXAMPLE 1 from 5-amino-6-chloro-2-methylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 1, Step 5) and {[1-(3-methoxy-2,2-dimethylpropyl)piperidin-4-yl]methyl}amine (EXAMPLE 9, Step 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07012080B2
Source datasetuspto-grants-2006_03
ORD IDord-6f2cc9301c5c450d8dcbbfdf5e48aba9
Source noteuspto-grants-2006_03