反应详情

The compound obtained in Step c (55 mg) was dissolved in methylene chloride (2 ml), added with triethylamine (56 μl and added with n-heptanoyl chloride (39 μl, produced by Tokyo Kasei Kogyo). The reaction mixture was stirred at room temperature for 30 minutes, diluted with methylene chloride, washed with saturated aqueous sodium hydrogencarbonate, dried over magnesium sulfate and concentrated. The resulting residue was applied on a silica gel column and eluted with hexane/ethyl acetate (3:2) to obtain the title compound (47.3 mg).

1. washwashed with saturated aqueous sodium hydrogencarbonate
2. dry with materialdried over magnesium sulfate
3. concentrationconcentrated
4. washeluted with hexane/ethyl acetate (3:2)