HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydrazinopyridine → 5-Methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Reactant | Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester | HCID 97734 | — |
| Product | 5-Methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylic acid | HCID 16777624 | 63.1% |
Reaction Steps
By the reaction and treatment in the same manner as in Starting Material Synthesis Example 1 using 2-pyridylhydrazine (8.0 g) and ethyl 2-ethoxymethyleneacetoacetate (13.7 g), the title compound (9.4 g) was obtained, melting point: 165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07015218B1 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-2ef67f870bff4383a39557e6c01db013 |
| Source note | uspto-grants-2006_03 |