Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1744548Generated: October 25, 2026

2-Chloro-5-nitrobenzotrifluoride → 4-(4-Morpholinopiperidin-1-yl)-3-trifluoromethylaniline

https://huagongshe.com/reaction/1744548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitrobenzotrifluorideHCID 61213—
Reactant4-MorpholinopiperidineHCID 795724—
Product4-(4-Morpholinopiperidin-1-yl)-3-trifluoromethylanilineHCID 22227917—

Reaction Steps

By the reaction and treatment in the same manner as in Starting Material Synthesis Example 40 using 4-chloro-3-trifluoromethylnitrobenzene and 4-morpholinopiperidine, the title compound was obtained, melting point: 118–120° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07015218B1
Source datasetuspto-grants-2006_03
ORD IDord-bfc87880b6024ba68ba3b771435ca774
Source noteuspto-grants-2006_03