1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-Chlorophenyl)-N-{3-cyano-4-[4-(2-methoxyethylamino)piperidin-1-yl]phenyl}-5-methylpyrazole-4-carboxamide

Participants

Reaction Steps

By the reaction and treatment in the same manner as in Example 151 using 1-(4-chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (0.6 g) and 5-amino-2-[4-[N-tert-butoxycarbonyl-N-(2-methoxyethyl) amino]piperidin-1-yl]benzonitrile (0.9 g), the title compound (0.6 g) was obtained, melting point: 194° C.

Provenance & Evidence