Potassium Cation → 3-Cyclopentyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]prop-2-enenitrile

HRID 174486Notes

Reaction equation

HRID 174486 reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[CH:23]1([C:28]#[C:29][C:30]#[N:31])[CH2:24][CH2:25][CH2:26][CH2:27]1.[K+:41].[K+:42].[nH:1]1[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1>>[n:1]1([C:28]([CH:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)=[CH:29][C:30]#[N:31])[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 426313464-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidineHCID 574776163-Cyclopentylpropiolonitrile

Product 1

HCID 665974453-Cyclopentyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]prop-2-enenitrile

Sources & evidence

ORD record
ord-47ccbc3229904c8d9ccd42806fd3adb1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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