HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-9-ethylcarbazole → (2S, 4EZ)-4-(cyanomethylene)-N-(9-ethyl-9H-carbazol-3yl)-1-(4-phenoxybenzoyl)-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-9-ethylcarbazole | HCID 8588 | — |
| Reactant | 4-Phenoxybenzoyl chloride | HCID 74193 | — |
| Reactant | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(cyanomethylene)-2-pyrrolidinecarboxylic acid | HCID 69250314 | — |
| Product | (2S, 4EZ)-4-(cyanomethylene)-N-(9-ethyl-9H-carbazol-3yl)-1-(4-phenoxybenzoyl)-2-pyrrolidinecarboxamide | HCID 69250533 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(cyanomethylene)-2-pyrrolidinecarboxylic acid, 4-phenoxybenzoyl chlo-ride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 37% purity by LC/MS. MS(ESI+): m/z=541.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018988B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-a94edf5b618a47e1bfdaeee37fd5bbb7 |
| Source note | uspto-grants-2006_03 |