Furfurylamine → HCID 131725481, compound

HRID 1745131Notes

Reaction equation

HRID 1745131 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)[CH2:10][C@H:9]1[C:24]([OH:26])=O)=[O:7])(C)(C)C.C(Cl)(=O)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1.[O:36]1[CH:40]=[CH:39][CH:38]=[C:37]1[CH2:41][NH2:42]>>[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=2)[CH2:10][C@H:9]1[C:24]([NH:42][CH2:41][C:37]1[O:36][CH:40]=[CH:39][CH:38]=1)=[O:26])(=[O:7])[C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

Participants

4

Reactant 3

HCID 3438FurfurylamineHCID 7412Benzoyl chlorideHCID 58714542HCID 58714542, compound

Product 1

HCID 131725481HCID 131725481, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(4-methoxybenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid, benzoyl chloride, and 2-furylmethylamine the title compound was obtained in 40% purity by LC/MS. MS(ESI+): m/z=448.2.

Sources & evidence

ORD record
ord-71ff3158ef3a4507a677d6ab139de50c
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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