Methyl Ethyl Ketone → 2-Bromoethyl cinnamate

Participants

Reaction Steps

83.3 g (0.5 mol) of cinnamic acid chloride and 200 mL of methyl ethyl ketone were placed in a reaction vessel. 62.5 g (0.5 mol) of 2-bromoethanol and 50 g of pyridine were added dropwise in the reaction vessel. The solution was refluxed with stirring for 2 hours under a nitrogen atmosphere and then concentrated. 100 mL of water was added to the concentrated solution. After extraction with chloroform, dehydration with anhydrous sodium sulfate, concentration, and drying, 121 g of 2-bromoethyl cinnamate was obtained.

Provenance & Evidence