反应详情

83.3 g (0.5 mol) of cinnamic acid chloride and 200 mL of methyl ethyl ketone were placed in a reaction vessel. 62.5 g (0.5 mol) of 2-bromoethanol and 50 g of pyridine were added dropwise in the reaction vessel. The solution was refluxed with stirring for 2 hours under a nitrogen atmosphere and then concentrated. 100 mL of water was added to the concentrated solution. After extraction with chloroform, dehydration with anhydrous sodium sulfate, concentration, and drying, 121 g of 2-bromoethyl cinnamate was obtained.

1. temperatureThe solution was refluxed
2. concentrationconcentrated
3. addition100 mL of water was added to the concentrated solution
4. extractionAfter extraction with chloroform, dehydration
5. concentrationwith anhydrous sodium sulfate, concentration
6. customdrying