Pyridine → HCID 22226281, compound

Participants

Reaction Steps

2.4 g of 1-bromomethylcyclopropylketone and 5.8 cm3 of pyridine are introduced into a three-necked flask containing 40 cm3 of ethanol and then the mixture is heated for 2 hours under reflux. After concentrating to dryness at 40° C. under reduced pressure (2.7 kPa), the residue is taken up in twice 30 cm3 of diethyl. ether. After filtration, washing with diethyl ether, the precipitate is dried under reduced pressure (90 Pa) to give 3.4 g of 1-cyclopropylcarbonylmethylpyridinium bromide in the form of a cream-coloured solid melting at 160° C.

Provenance & Evidence