1-Chloro-2-iodobenzene → (2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 1745460ノート

反応式

HRID 1745460 の反応式
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.[Cl:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=1I>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=2[Cl:37])=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 3

HCID 119931-Chloro-2-iodobenzeneHCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

生成物 1

HCID 69592813(2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

実験手順

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and l-chloro-2-iodobenzene according to the general procedure C. Obtained as a yellow oil (886 mg).

出典と根拠

ORDレコード
ord-e9d6b1d56e3c48428a8754d0af4aac0f
出典データセット
uspto-grants-2006_03
特許番号
US07018998B2

反応ノート

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