HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (4'-fluoro-3-nitro-[1,1'-biphenyl]-4-YL)carbamate → Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (4'-fluoro-3-nitro-[1,1'-biphenyl]-4-YL)carbamate | HCID 69592758 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate | HCID 59737201 | — |
Reaction Steps
Prepared from (4′-fluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example B12) by catalytic hydrogenation with Raney-Nickel according to the general procedure G (method a). Obtained as a light yellow solid (3.40 g). MS (ISP) 303 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-74ffff8d3ec14a96b81d38921a6604d8 |
| Source note | uspto-grants-2006_03 |