HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22224949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | {3-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-3'-methyl-biphenyl-4-yl}-carbamic acid tert.-butyl ester | HCID 86588004 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22224949 | HCID 22224949 | — |
Reaction Steps
Prepared from {3-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-3′-methyl-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K15) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a light yellow powder (145 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-bf94704a7f704b128b138092cad7b1be |
| Source note | uspto-grants-2006_03 |