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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745733Generated: October 30, 2026

Trifluoroacetic acid → HCID 22224632, compound

https://huagongshe.com/reaction/1745733

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86588046HCID 86588046—
SolventDichloromethaneHCID 6344—
ProductHCID 22224632HCID 22224632—

Reaction Steps

Prepared from {3-[3-(3-chloro-thiophen-2-yl)-3-oxo-propionylamino]-4′-fluoro-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K61) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a yellow solid (232 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-1026bef08ac7438286a1914b350d6545
Source noteuspto-grants-2006_03