Acetic Acid → Cyclooctanone

Participants

Reaction Steps

To 7.5 ml of acetic acid were added 336 mg (3.0 mmol) of cyclooctane, 60 mg (0.3 mmol) of N-hydroxysaccharin and 3.9 mg (0.015 mmol) of acetylacetonatocobalt Co(acac)2. The resultant mixture was stirred under an oxygen atmosphere at a temperature of 100° C. for 6 hours. The products in the reaction mixture were analysed by gas chromatography, with cyclooctane being transformed, with a conversion of 88%, into cyclooctanone (selectivity 42%, yield 37%), cyclooctanol (selectivity 3%, yield 2.5%), 1,4-cyclooctanedione (selectivity 11.5%, yield 10%) and octanediacid (selectivity 18%, yield 16%).

Provenance & Evidence