HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178466584, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-Methyl-2-(1-[9-(2-trimethylsilylethoxymethyl)-9H-purin-6-ylamino]ethyl)-3-(3-trimethylsilylethynyiphenyl)-3H-quinazolin-4-one | HCID 67103558 | — |
| Product | HCID 178466584 | HCID 178466584 | — |
Reaction Steps
Compound 139 was treated with 4N HCl in MeOH at 70° C. for 16 hours in accordance with the procedure described for compound 0.121 (step D). This reaction afforded compound 144, the structure of which is shown below. m/z=440 (M+H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09149477B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-dc069daa4d944a06a72f426e5e27d8ed |
| Source note | uspto-grants-2015_10 |