Tetrahydrofuran → 5-[6-(hydroxymethyl)-1H-imidazo[4,5-c]pyridin-1-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14][cH:15][n:16]2-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]2[c:29]([C:34]([F:35])([F:36])[F:37])[cH:30][cH:31][cH:32][cH:33]2)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1)([CH3:5])([CH3:38])[CH3:39].[CH2:41]([N+:42]([CH2:43][CH2:44][CH2:45][CH3:46])([CH2:47][CH2:48][CH2:49][CH3:50])[CH2:51][CH2:52][CH2:53][CH3:54])[CH2:55][CH2:56][CH3:57].[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[F-:40]>>[OH:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14][cH:15][n:16]2-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]2[c:29]([C:34]([F:35])([F:36])[F:37])[cH:30][cH:31][cH:32][cH:33]2)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1bfc29d48b1d4979b503069d3a6d0a2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…