HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Sodium Nalpha-[3-(2,6-Difluorophenyl)acryloyl]-L-Tryptophanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl Nalpha-[3-(2,6-Difluorophenyl)acryloyl]-L-Tryptophanate | HCID 86655446 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Sodium Nalpha-[3-(2,6-Difluorophenyl)acryloyl]-L-Tryptophanate | HCID 86655492 | 68% |
Reaction Steps
The same procedures as in Example 60 were carried out from the compound obtained in Example 13 (3.9 g), 1 mol/L of an aqueous sodium hydroxide solution (15 mL), and methanol (150 mL), to give the captioned compound (2.7 g, 68%) as an amorphous solid product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150510B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-cce4a6d800b7490e9be972fd4d5ed303 |
| Source note | uspto-grants-2015_10 |