Sodium ion → tert-Butyl ethyl (5-nitropyridin-2-yl)malonate

HRID 174665Notes

Reaction equation

HRID 174665 reaction equation
[C:13]([CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])(=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[Cl:1][c:2]1[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[H-:11].[Na+:12]>>[c:2]1([CH:14]([C:13](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[C:15](=[O:16])[O:17][CH2:18][CH3:19])[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 783082-Chloro-5-nitropyridineHCID 96345tert-Butyl ethyl malonateHCID 166653Hydride

Product 1

HCID 54383765tert-Butyl ethyl (5-nitropyridin-2-yl)malonate

Sources & evidence

ORD record
ord-8335b3138af545aeb0e98ecc0a69dac9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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