4-Amino-2-chlorophenol → HCID 25182744, compound

HRID 1746692Notes

Reaction equation

HRID 1746692 reaction equation
[CH:1]1([NH:7][C:8]2[N:13]=[CH:12][N:11]=[C:10]([C:14]([OH:16])=O)[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[C:20]([Cl:25])[CH:19]=1>ClCCl>[Cl:25][C:20]1[CH:19]=[C:18]([NH:17][C:14]([C:10]2[CH:9]=[C:8]([NH:7][CH:1]3[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]3)[N:13]=[CH:12][N:11]=2)=[O:16])[CH:23]=[CH:22][C:21]=1[OH:24]

Participants

4

Reactant 2

HCID 775784-Amino-2-chlorophenolHCID 594470756-(Cyclohexylamino)pyrimidine-4-carboxylic acid2×

Product 1

HCID 25182744HCID 25182744, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 4-amino-2-chlorophenol (Aldrich), the title compound was obtained as a white solid after trituration in dichloromethane.

Sources & evidence

ORD record
ord-1d476c07e9fd47b293b58ee9ee1cbe67
Source dataset
uspto-grants-2015_10
Patent number
US09150519B2

Reaction notes

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