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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1746742Generated: November 1, 2026

4-Amino-3-methylbenzene-1-sulfonamide → N-[4-(aminosulfonyl)-2-methylphenyl]-6-(cyclohexyloxy)pyrimidine-4-carboxamide

https://huagongshe.com/reaction/1746742

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-3-methylbenzene-1-sulfonamideHCID 143037—
Reactant6-(Cyclohexyloxy)pyrimidine-4-carboxylic acidHCID 59447062—
ProductN-[4-(aminosulfonyl)-2-methylphenyl]-6-(cyclohexyloxy)pyrimidine-4-carboxamideHCID 25182912—

Reaction Steps

Following the general method as outlined in Example 1, starting 6-(cyclohexyloxy)pyrimidine-4-carboxylic acid (Intermediate 32) and 4-amino-3-methylbenzenesulfonamide (Biofine), the title compound was obtained as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150519B2
Source datasetuspto-grants-2015_10
ORD IDord-3aaac8420bb94a6baafd610f17c218c5
Source noteuspto-grants-2015_10