HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-(2-Nitro-phenylamino)-hexanoic acid ethyl ester → (S)-3-(2-Amino-phenylamino)-hexanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-(2-Nitro-phenylamino)-hexanoic acid ethyl ester | HCID 59497566 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (S)-3-(2-Amino-phenylamino)-hexanoic acid ethyl ester | HCID 59497425 | — |
Reaction Steps
To a solution of (S)-3-(2-Nitro-phenylamino)-hexanoic acid ethyl ester (795 mg, 2.8 mmol) in EtOH (20 mL) was added Pd/C (10% wt on carbon) (300 mg). The solution was stirred at room temperature for 3 hours. The solution was filtered and the filtrate was concentrated. The residue (683 mg, 96%) was used in the next step of the synthesis without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150556B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-82ac7aa32dfe417f86dac980a5ae2426 |
| Source note | uspto-grants-2015_10 |