HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-(2-nitro-phenylamino)-propionic acid tert-butyl ester → HCID 59497586, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-(2-nitro-phenylamino)-propionic acid tert-butyl ester | HCID 59497651 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59497586 | HCID 59497586 | 100% |
Reaction Steps
A mixture of 2-methyl-2-(2-nitro-phenylamino)-propionic acid tert-butyl ester (638 mg, 2.3 mmol), 10% Pd/C (110 mg) in EtOH (25 mL) under H2 atmosphere at room temperature was stirred for 30 min. The reaction mixture was filtered and the organic layer was concentrated to give the desired 2-(2-amino-phenylamino)-2-methyl-propionic acid tert-butyl ester (570 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150556B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-09e0868281784916bad716eda4ebc45d |
| Source note | uspto-grants-2015_10 |