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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1747772Generated: October 31, 2026

HCID 89586209, compound → HCID 89586214, compound

https://huagongshe.com/reaction/1747772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 89586209HCID 89586209—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 89586214HCID 8958621430%

Reaction Steps

A solution of 6-[(benzyloxy)methyl]-1-(2-tert-butoxyphenyl)-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one (0.89 g) in TFA (9 mL) was heated under reflux for 4 hr. After cooling, the solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/methanol) to give the title compound (0.19 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150588B2
Source datasetuspto-grants-2015_10
ORD IDord-545f14e67cb44f7b97c733808a500c2f
Source noteuspto-grants-2015_10