Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 66749880 | HCID 66749880 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66749795 | HCID 66749795 | — |
Reaction Steps
To a mixture of tert-butyl 5-(2,2-dioxido-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazin-9-yl)-1H-indole-1-carboxylate (500 mg) in THF (dry) (80 mL) was added 8 M NaOH aq. (8 mL). The mixture was stirred at 50° C. for 30 min. MeOH (20 mL) was added and the mixture was stirred at 50° C. for 4 hr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09150591B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-376671b79921463fb604e13d58cf43d7 |
|---|
| Source note | uspto-grants-2015_10 |
|---|
