HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748196Generated: October 30, 2026
Methanol → Methyl 2-hydroxypyrrolo[1,2-b]pyridazine-6-carboxylate
https://huagongshe.com/reaction/1748196
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 178524046 | HCID 178524046 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | Methyl 2-hydroxypyrrolo[1,2-b]pyridazine-6-carboxylate | HCID 178496938 | — |
Reaction Steps
The semi-crude material from above, 2-Hydroxypyrrolo[1,2-b]pyridazine-6-carboxylic acid (100 mg, 0.56 mmol) was dissolved in methanol (5 mL) and concentrated sulfuric acid (2 drops). The solution was heated to 80° C. for 4 hours, and then the solvent evaporated in vacuo. The crude material was used directly in the next step. MS m/z 193.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09150568B2 |
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| Source dataset | uspto-grants-2015_10 |
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| ORD ID | ord-a4ca24f32e1547ada81293a2e03aeead |
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| Source note | uspto-grants-2015_10 |
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