2-Aminothiophenol → HCID 136483032, compound

HRID 1748422Notes

Reaction equation

[C:1]([C:5]1[C:6]([OH:17])=[C:7]([CH:10]=[C:11]([C:13]([CH3:16])([CH3:15])[CH3:14])[CH:12]=1)[CH:8]=O)([CH3:4])([CH3:3])[CH3:2].[NH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[SH:25]>C1C=CC=CC=1>[SH:25][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[N:18]=[CH:8][C:7]1[CH:10]=[C:11]([C:13]([CH3:16])([CH3:15])[CH3:14])[CH:12]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:6]=1[OH:17]

Participants

Conditions

Temperature: 100 °C

Procedure

A solution of 3,5-di-tert-butyl-2-hydroxybenzaldehyde (6.79 g, 0.03 mol) in benzene (50 mL) was added to a solution of 2-Aminothiophenol (3.63 g, 0.03 mol) in benzene (50 mL) and heated at 100° C. in closed glass vessel for 3 days. The solvent was removed in vacuum. The product was obtained as a yellow oil in a quantitative yield.

Workup

customThe solvent was removed in vacuum
customThe product was obtained as a yellow oil in a quantitative yield

Sources & evidence

ORD record: ord-2a3b5f9d65c14c5997cebff1c5831674
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09150676B2

Reaction notes

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