Sodium Hydroxide → HCID 86692423, compound

Participants

Reaction Conditions

Reaction Steps

1N Aqueous solution of sodium hydroxide (7.0 ml) was added at room temperature to a solution of 1-[4-(methoxymethyl)phenyl]-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester (401 mg) in ethanol (14 ml) and stirred at 70° C. for two hours. After completion of the reaction, ethanol was evaporated, water and 1N hydrochloric acid aqueous solution was added therein and the precipitated solid was collected by filtration to give the titled compound (314 mg) as a white solid.

Provenance & Evidence