Hydrazine hydrate (1:1) → 6-Hydrazinonicotinic acid

Participants

Reaction Steps

Hydrazine monohydrate (101 g) was added to a solution of 6-chloronicotinic acid (20 g) in ethanol (20 ml) at room temperature and stirred under reflux. After completion of the reaction, the solvent was evaporated, ethanol was added and the solid was collected by filtration to give 6-hydrazinonicotinic acid (13.8 g).

Provenance & Evidence