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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748578Generated: November 2, 2026

HCID 16794101, compound → HCID 178455310, compound

https://huagongshe.com/reaction/1748578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16794101HCID 16794101—
ReactantHCID 178455308HCID 178455308—
ProductHCID 178455310HCID 178455310—

Reaction Steps

trans-5-Bromo-2-[4-(tert-butyldimethylsilyloxy)cyclohex-1-yl]pyridine (1.54 g) described in Reference Example 103 (3) was used in place of 1-(5-bromopyridin-2-yl)-c-4-(tert-butyldimethylsilanyloxy)-r-1-cyclohexanecarbonitrile in Reference Example 144 (2) and (3), and reacted and treated in a similar manner to give the titled compound (1.11 g) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150555B2
Source datasetuspto-grants-2015_10
ORD IDord-5c0118ecbb4f4808b495d0f3aad4f9d8
Source noteuspto-grants-2015_10