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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748581Generated: October 31, 2026

HCID 16794101, compound → HCID 86692533, compound

https://huagongshe.com/reaction/1748581

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16794101HCID 16794101—
ReactantHCID 57803252HCID 57803252—
ProductHCID 86692533HCID 86692533—

Reaction Steps

8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol (3.0 g) described in Reference Example 76 (1) was used in place of 1-(5-bromopyridin-2-yl)-c-4-(tert-butyldimethylsilanyloxy)-r-1-cyclohexanecarbonitrile in Reference Example 144 (2) and (3), and reacted and treated in a similar manner to give the titled compound (1.28 g) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150555B2
Source datasetuspto-grants-2015_10
ORD IDord-dbcb282dea4045029335808c6acbe28e
Source noteuspto-grants-2015_10